Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027092
Disease: Myopia
Myopia
0.030 Biomarker disease BEFREE In this single-center case series, lenticules were obtained from patients undergoing SMILE for the correction of myopia and the lenticule patch graft was performed in three patients with limbal dermoid. 31735992 2020
CUI: C0011649
Disease: Dermoid Cyst
Dermoid Cyst
0.010 Biomarker disease BEFREE To report a novel technique to treat superficial limbal dermoid by using the corneal intrastromal lenticules obtained from SMILE and to evaluate the initial clinical outcomes of lenticule patch graft for treatment of limbal dermoid. 31735992 2020
CUI: C0027092
Disease: Myopia
Myopia
0.030 Biomarker disease BEFREE Comparative study of wave-front aberration and corneal Asphericity after SMILE and LASEK for myopia: a short and long term study. 30894159 2019
Nasal Type Extranodal NK/T-Cell Lymphoma
0.030 GeneticVariation disease BEFREE <b>Conclusion</b>: Our analysis confirms that SMILE regimen, which is current standard to treat advanced-stage ENKTL may be associated with more severe hematological toxicity compared to other L-asparaginase combinations, including methotrexate-based (AspaMetDex, MESA and MEDA) or gemcitabine-based (GELOX, PGEMOX, DDGP, GDL, GOLD, GLIDE) or CCRT-based regimens. 30449214 2019
CUI: C0018801
Disease: Heart failure
Heart failure
0.020 Biomarker disease BEFREE The present subgroup analysis from the post-marketing surveillance SMILE Study aims to explore the efficacy and safety of tolvaptan across the HF subgroups (HFrEF, HFpEF, and HFmrEF).Patients with HF accompanied by fluid retention who received tolvaptan were enrolled. 31484861 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.020 Biomarker disease BEFREE The present subgroup analysis from the post-marketing surveillance SMILE Study aims to explore the efficacy and safety of tolvaptan across the HF subgroups (HFrEF, HFpEF, and HFmrEF).Patients with HF accompanied by fluid retention who received tolvaptan were enrolled. 31484861 2019
CUI: C0004106
Disease: Astigmatism
Astigmatism
0.010 Biomarker disease BEFREE Clinical outcomes and vector analysis of astigmatism were reviewed and compared between wavefront-guided laser in situ keratomileusis (LASIK) (WFG group) (STAR S4 IR with iDesign aberrometer; Johnson & Johnson Vision Care, Inc., Santa Ana, CA), topography-guided LASIK (TOPO group) (Allegretto Wave Eye-Q laser; Alcon Laboratories, Inc., Fort Worth, TX), and small incision lenticule extraction (SMILE group) (VisuMax laser; Carl Zeiss Meditec AG, Jena, Germany). 31710370 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.010 GeneticVariation disease BEFREE Factors associated with improvement in symptoms and quality of life for first-line EGFR-tyrosine kinase inhibitor treatment in patients with <i>EGFR</i>-mutated non-small-cell lung cancer - A multicenter prospective SMILE study. 31417660 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.010 Biomarker disease BEFREE Targeting HDAC4, HIF-1α and CREBZF may be considered in treatment of ovarian cancer with p53 and RAS mutations. 30867818 2019
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.010 Biomarker disease BEFREE Targeting HDAC4, HIF-1α and CREBZF may be considered in treatment of ovarian cancer with p53 and RAS mutations. 30867818 2019
CUI: C1318485
Disease: Liver regeneration disorder
Liver regeneration disorder
0.010 AlteredExpression phenotype BEFREE In contrast, adeno-associated virus mediated overexpression of CREBZF in the liver inhibits the expression of cyclin gene family and attenuates liver regeneration in CCl<sub>4</sub> -treated mice. 31469186 2019
CUI: C4721610
Disease: Carcinoma, Ovarian Epithelial
Carcinoma, Ovarian Epithelial
0.010 Biomarker disease BEFREE Targeting HDAC4, HIF-1α and CREBZF may be considered in treatment of ovarian cancer with p53 and RAS mutations. 30867818 2019
CUI: C0027092
Disease: Myopia
Myopia
0.030 Biomarker disease BEFREE A retrospective case series was conducted at Eye subspecialty center, Cairo, Egypt on 9 eyes with myopia or myopic astigmatism (spherical equivalent - 8.0 and - 12.0D). undergoing SMILE procedure and needed second interference. 29454328 2018
CUI: C0018801
Disease: Heart failure
Heart failure
0.020 GeneticVariation disease BEFREE Efficacy and Safety of Zofenopril Versus Ramipril in the Treatment of Myocardial Infarction and Heart Failure: A Review of the Published and Unpublished Data of the Randomized Double-Blind SMILE-4 Study. 29667144 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.020 GeneticVariation disease BEFREE Efficacy and Safety of Zofenopril Versus Ramipril in the Treatment of Myocardial Infarction and Heart Failure: A Review of the Published and Unpublished Data of the Randomized Double-Blind SMILE-4 Study. 29667144 2018
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 Biomarker group BEFREE Thus, we identified three miRNAs (hsa-miR-421, hsa-miR-29b-1-5p, and hsa-miR-27b-5p) with two mRNAs (FBXO11 and CREBZF) that might play an important role in the GC development from premalignant adenomas. 29725252 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 Biomarker disease BEFREE Smartphone problem-solving and behavioural activation therapy to reduce fear of recurrence among patients with breast cancer (SMartphone Intervention to LEssen fear of cancer recurrence: SMILE project): protocol for a randomised controlled trial. 30413519 2018
CUI: C0013238
Disease: Dry Eye Syndromes
Dry Eye Syndromes
0.010 Biomarker disease BEFREE A new type of corneal refractive surgery, SMILE, which has less impact on corneal nerves, induces less postoperative dry eye, supporting the association between corneal denervation and postoperative dry eye. 30481814 2018
CUI: C0014544
Disease: Epilepsy
Epilepsy
0.010 Biomarker disease BEFREE To determine the effectiveness and cost-effectiveness of Self-Management education for people with poorly controlled epILEpsy [SMILE (UK)]. 29717699 2018
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.010 AlteredExpression disease BEFREE Hepatic CREBZF couples insulin to lipogenesis by inhibiting insig activity and contributes to hepatic steatosis in diet-induced insulin-resistant mice. 29637572 2018
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.010 Biomarker disease BEFREE Thus, we identified three miRNAs (hsa-miR-421, hsa-miR-29b-1-5p, and hsa-miR-27b-5p) with two mRNAs (FBXO11 and CREBZF) that might play an important role in the GC development from premalignant adenomas. 29725252 2018
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.010 GeneticVariation disease BEFREE Efficacy and Safety of Zofenopril Versus Ramipril in the Treatment of Myocardial Infarction and Heart Failure: A Review of the Published and Unpublished Data of the Randomized Double-Blind SMILE-4 Study. 29667144 2018
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions
0.010 Biomarker group BEFREE Thus, we identified three miRNAs (hsa-miR-421, hsa-miR-29b-1-5p, and hsa-miR-27b-5p) with two mRNAs (FBXO11 and CREBZF) that might play an important role in the GC development from premalignant adenomas. 29725252 2018
CUI: C0233705
Disease: Cancerophobia
Cancerophobia
0.010 Biomarker disease BEFREE Smartphone problem-solving and behavioural activation therapy to reduce fear of recurrence among patients with breast cancer (SMartphone Intervention to LEssen fear of cancer recurrence: SMILE project): protocol for a randomised controlled trial. 30413519 2018
CUI: C0271183
Disease: Severe myopia
Severe myopia
0.010 Biomarker disease BEFREE Forty-three eyes with high myopia and thin corneas were enrolled.All eyes underwent SMILE procedure. 28963702 2018